11 October 2018: The Global Fluorescence
Lifetime Imaging Microscopy Market, by end-user, is segmented
into semiconductor, chemical industry, medical care, academic institutes, and
so on. Fluorescence lifetime imaging microscopy (FLIM) is a technique utilized
to measure the fluorescence lifetime of molecules. The fluorescence lifetime is
the average time a molecule spends in an excited state before returning to the
ground state. This measurement is a highly quantitative value that can be used
to determine molecular dynamics with nanoscale resolution. FLIM is a standard
technique for determining the lifetimes of fluorescent molecules in cells,
tissues and whole animal models. Fluorescence lifetime imaging microscopy
(FLIM) produces an image based on the differences in the excited state decay
rate from a fluorescent sample. Thus, FLIM is a fluorescence imaging technique
where the contrast is based on the lifetime of individual fluorophores rather
than their emission spectra. The fluorescence lifetime is defined as the
average time that a molecule remains in an excited state prior to returning to
the ground state by emitting a photon.
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Multi-color staining with
fluorescent dyes is actively used for observing the distribution of biological
materials (such as proteins, lipids, nucleic acids, and ions) in the field of
tissue and cell research. The detection technology for fluorescence observation
has advanced to a level at which a single fluorescent dye molecule can be
detected under the best of circumstances. Rising global focus on
nanotechnology, appropriate government and corporate funding and technological advancements
such as super resolution microscopy; high-throughput techniques and
digitization of microscopes are the factors driving the fluorescence lifetime
imaging microscopy market.
However, the high cost of
advanced microscopes; implementation of excise tax by the U.S. government; and
the heavy custom duty with respect to medical devices are hindering the growth
of this market. On the other hand, novel application areas such as ontogenetic
and high potential emerging markets such as Middle East, China, and Japan
represent significant growth opportunities for the key players.
Further, time consuming sample
preparation process for advanced microscopes and requirement of high degree of
technical expertise to handle complex microscopes may prove to be a restraint
to the growth of this market during the forecast period. The fluorescence
lifetime imaging microscopy market is segmented on the basis of application and
geography. On the basis of application, the fluorescence lifetime imaging
microscopy market is segmented into North America, Asia Pacific, Europe, Latin
America and Middle East & Africa. North America is expected to account for
the largest share of the microscopy market, followed by Europe.
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However, Asia Pacific is expected
to register a higher growth rate during the forecast period, owing to huge
investment opportunities in this region. The growth of the fluorescence
lifetime imaging microscopy market in the Asia Pacific region will be
attributed toIndia, Australia, China,and countries in the Middle East. The key
players of fluorescence lifetime imaging microscopy are Leica microsystems,
Brucker, Fly limited, Olympus Corporation, Asylum, Japanese Electronics Co.
Ltd., Micro engineering in Denmark, Hitachi High-Technologies Corporation, Carl
Zeiss AG and Nikon Corporation.
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