In the recent years, organ transplantation has rapidly advanced as a therapeutic interpolation that is lifesaving as well as greatly funds to a better quality of life to organ beneficiaries. The rapid development has been made possible due to extreme growth in the immunosuppressive stock. However, the side effects of these drugs can be severe, which is one the reasons that life expectancy of patients still considerably falls short. Immunosuppressant’s are a cluster of drugs that are utilized to suppress the immune response through several biological mechanisms. In case of organ transplantation, immunosuppressants are basically utilized to inhibit the attack or recognition of the imported organ via several immune responses. They should be used only under administration of expertise.
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At times there may be also
side-effects accompanied by immunosuppressant drugs such as increased proneness
of infection, overdue wound healing, dyspepsia, etc. The factors that propel
the growth of the Organ Transplant and Immunosuppressant Drug Market include
rising frequency of chronic diseases, expanding number of organ donor,
effective method for treatment of end-stage organ failure, high demand for
organ transplant. This consequently gives rise to a high demand for
immunosuppressant drugs to avoid organ rejection after transplantation. On the
other hand, there are factors that hinder the growth of the market like
expenditure of organ transplantation, post transplantation problems, and risk
of infection. The Organ Transplant and Immunosuppressant Drug Market is
categorized based on drugs, transplant areas, and geography.
On the basis of drugs, the Organ
Transplant and Immunosuppressant Drug Market is categorized as pyrimidine
synthesis (DHODH) inhibitors (leflunomide, azathioprine), depleting antibodies
(horse or rabbit antithymocyte globulin, muromonab-CD3, alemtuzumab,
rituximab), non-depleting antibodies and fusion proteins (daclizumab,
basiliximab, belatacept), purine synthesis (IMDH) inhibitors (mycophenolatemofetil,
enteric-coated mycophenolic acid (EC-MFS), mizoribine (MZR)), protease
inhibitor (bortezomib), C5 inhibitor (eculizumab), calcineurin inhibitors
(cyclosporine, tacrolimus), and mTOR inhibitors (sirolimus, everolimus).
On the basis of transplant areas,
the Organ Transplant and Immunosuppressant Drug Market is categorized as heart,
kidney, lung, liver, and pancreas. In 2014, the demand was the highest for
immunosuppressant drugs utilized through kidney transplant. During the forecast
period kidney transplant sector is anticipated to account for the largest the
market due to cost effectiveness than persistent period of dialysis, rise of
kidney transplants, and so on.
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Based on geography, the Organ
Transplant and Immunosuppressant Drug Market is categorized as North America,
Europe, Asia Pacific, and Rest of the World. In 2014, North America dominated
the global Organ Transplant Immunosuppressant Drug Market owing to the greater
number of organ transplants carried out within as well as sophisticated medical
facilities such as technology development, immunosuppressant drug discovery,
surgical techniques and healthcare structure. North America is anticipated to
be the fastest growing region followed by Europe. Some of the prominent
players that fuel the growth of the Organ Transplant Immunosuppressant Drug
Market include Astellas Pharma, Accord Healthcare Ltd., Inc., Novartis AG,
Pfizer, Inc., Sanofi, Genzyme Corporation, Watson Pharmaceuticals Inc.,Mylan
Laboratories, Inc., GlaxoSmithKline plc, and Hoffman La Roche.
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