Global LCMS
Market is segmented on the basis of product types, application, and region.
Liquid chromatography is a fundamental separation technique in the life
sciences and related fields of chemistry. Unlike gas chromatography, which is
unsuitable for nonvolatile and thermally fragile molecules, liquid
chromatography can safely separate a very wide range of organic compounds, from
small-molecule drug metabolites to peptides and proteins. LCMS stands for
Liquid Chromatography/Mass Spectrometry. It refers to the combination of liquid
chromatographic separation with mass spectrometric detection.
Liquid Chromatography Mass
Spectrometry (LCMS) is an analytical chemistry laboratory technique for
identification, quantitation and mass analysis of materials. This technique
consents for the structural interpretation of unknown molecules through
fragmentation. Similar to HPLC, Liquid Chromatography Mass Spectrometry
utilizes a compound’s intrinsic affinity for both a “mobile phase” (typically a
buffered solvent) and a “stationary phase” (porous solid support with
specialized coating).
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Market Report at :
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Basically, a pump is used to
provide a continuous flow of a solvent into which a dissolved sample is
introduced. Once the sample is in the solvent flow, it travels through an
analytical column. The compounds present in the sample mixture are then
separated depending on their affinity to the coated particles in the column.
After the components in the sample are separated, they pass through a mass
detector. The mass detector response and the “retention time” of the
compound(s) of interest may then be compared to a reference material.
On the basis of type, (Liquid
Chromatography Mass Spectrometry) LCMS market is classified as Single
Quadrupole LC-MS, Triple Quadrupole LC-MS, and Ion Trap LC-MS. Single
Quadrupole LC-MS – robust and reliable mass detection technique for many
different functional areas of LC-MS across many different industries. Designed
for compatibility with UPLC, UPSFC, HPLC, and Auto Purification, and with a
wide range of ionization options, single quadrupole mass detection easy way to
generate an extra dimension of information from separation.
Triple Quadrupole LC-MS –also
known as QqQ, is a tandem MS method in which the first and third quadrupole act
as mass filters and the second causes fragmentation of the analyte through
interaction with a collision gas, it is a radiofrequency- only quadrupole, and
can be used in either SIM or scan mode. Ion Trap LC-MS – use three hyperbolic
electrodes to trap ions in a three-dimensional space using static and radio
frequency voltages. he two most common types of ion trap are the Penning trap,
which forms a potential via a combination of electric and magnetic fields, and
the Paul trap which forms a potential via a combination of static and
oscillating electric fields.
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LCMS Market at: https://www.millioninsights.com/industry-reports/liquid-chromatography-mass-spectrometry-lcms-market/request-sample
On the basis of product types,
the (Liquid Chromatography Mass Spectrometry) LCMS market is classified as
HPLC, RPLC, and NPLC. Methods in which the stationary phase is more polar than
the mobile phase are termed as “Normal Phase Liquid Chromatography (NPLC)” and
the opposite is termed as “Reversed Phase Liquid Chromatography (RPLC). NPLC -
that separate molecules depending on their polarity, these columns are made out
of silica with polar functional groups covalently attached, polar molecules
take longer to pass through these columns because they are attracted to it
through dipole-dipole interactions. On the basis of applications, the (Liquid
Chromatography Mass Spectrometry) LCMS market is classified as
pharmacokinetics, Proteomics/metabolomics, Drug development, and others
(protein characterization, targeted peptide quantification, Lipidomics, small
molecule drug research). Geographically, the (Liquid Chromatography Mass
Spectrometry) LCMS market is segmented into North America, Europe, Japan, Latin
America, India, and ROW.
The key players in the (Liquid
Chromatography Mass Spectrometry) LCMS market are Hitachi, Shimadzu, Thermo
Fisher Scientific, AB Sciex., Bruker, Waters, Agilent Technologies, Gilson,
Agela Technologies, Indigo BioSystems, JASCO, and Jiangsu Skyray Instrument
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